Publications

Romu T, Håkansson VC, Leinhard OD, Tallberg J, Dahlström N, Persson A, Heglind M, Lidell ME, Enerbäck S, Borga M, Nystrom FH (2016) A Randomized Trial of Cold-Exposure on Energy Expenditure and Supraclavicular Brown Adipose Tissue Volume in Humans. Metabolism, 65 (6), pp. 926-934.

Borga M, West J, Bell JD, Harvey NC, Romu T, Heymsfield SB, Leinhard OD (2018) Advanced body composition assessment: from body mass index to body composition profiling, Journal of Investigative Medicine, DOI 10.1136/jim-2018-000722

Linge, J., Ekstedt, M., Dahlqvist Leinhard, O. (2020). Adverse muscle composition is linked to poor functional performance and metabolic comorbidities in NAFLD, JHEP Reports, doi: https://doi.org/10.1016/j.jhepr.2020.100197.

Noureddin M, et al., (2020) Attribution of Nonalcoholic Steatohepatitis as an Etiology of Cirrhosis for Clinical Trials Eligibility: Recommendations From the Multi-stakeholder Liver Forum, Gastroenterology. E1, August 01, 2020; Volume 159, Issue 2, P422-427

Karlsson A, Rosander J, Romu T, Tallberg J, Grönqvist A, Borga M, Leinhard OD (2015) Automatic and Quantitative Assessment of Regional Muscle Volume by Multi‐Atlas Segmentation Using Whole‐Body Water–Fat MRI. Journal of Magnetic Resonance Imaging, 41 (6), pp. 1558-1569. doi:10.1002/jmri.24726

Linge J, Borga M, West J, Tuthill T, Miller MR, Dumitriu A, Thomas EL, Romu T, Tunón P, Bell JD, Leinhard OD (2018) Body Composition Profiling in the UK Biobank Imaging Study, Obesity, doi:10.1002/oby.22210 

Petridou E, Kibiro M, Gladwell C, Malcolm P, Toms A, Juette A, Borga M, Leinhard OD, Romu T, Kasmai B, Denton E. (2017) Breast fat volume measurement using wide-bore 3 T MRI: comparison of traditional mammographic density evaluation with MRI density measurements using automatic segmentation. Clinical Radiology, 72, pp. 565 -572.

Neeland I, Poirier P, Després J-P, (2018) Cardiovascular and Metabolic Heterogeneity of Obesity Clinical Challenges and Implications for Management, Cardiovascular and Metabolic Heterogeneity of Obesity Clinical Challenges and Implications for Management, Circulation. 2018;137:1391-1406 

Romu T, Elander L, Leinhard OD, Lidell ME, Betz MJ, Persson A, Enerbäck S, Borga M (2015) Characterization of Brown Adipose Tissue by Water–Fat Separated Magnetic Resonance Imaging. Journal of Magnetic Resonance Imaging, 42 (6), pp. 1639-1645. doi:10.1002/jmri.24931

Andersson T, Romu T, Karlsson A, Norén B, Forsgren M, Smedby Ö, Kechagias S, Almer S, Lundberg P, Borga M, Leinhard OD (2015) Consistent Intensity Inhomogeneity Correction in Water-Fat MRI. Journal of Magnetic Resonance Imaging, 42 (2), pp. 468-476.

Gerdle B, Forsgren MF, Bengtsson A, Leinhard OD, Sören B, Karlsson A, Brandejsky V, Lund E, Lundberg P (2013) Decreased Muscle Concentrations of ATP And PCR in the Quadriceps Muscle of Fibromyalgia Patients - A 31P MRS Study. European Journal of Pain, DOI: 10.1002/j.1532-2149.2013.00284.

Abrahamson A, Rzepecka A, Romu, T, Borga M, Leinhard OD, Lundberg P, Kihlberg J, Dabrosin C. (2016) Dense Breast Tissue in Postmenopausal Women Is Associated With a Pro-Inflammatory Microenvironment in Vivo. OncoImmunology, 5 (10). 

Lidell M, Betz M, Leinhard OD, Heglind M, Elander L, Slawik M, Mussack T, Nilsson D, Romu T, Nuutila P, Virtanen K, Beuschlein F, Persson A, Borga M, Enerbäck S (2013) Evidence for Two Types of Brown Adipose Tissue in Humans. Nature Medicine, 19(5), pp. 631-634. doi:10.1038/nm.3017

Gerdle, B., Ghafouri, B., Lund, E., Bengtsson, A., Lundberg, P., Ettinger-Veenstra, H. van, Leinhard, O.D., Forsgren, M. F. (2020). Evidence of Mitochondrial Dysfunction in Fibromyalgia: Deviating Muscle Energy Metabolism Detected Using Microdialysis and Magnetic Resonance. Journal of Clinical Medicine, 9(11), 3527. doi:10.3390/jcm9113527

Peterson P, Romu T, Brorson H, Leinhard OD, Månsson S (2016) Fat Quantification in Skeletal Muscle Using Multigradient‐Echo Imaging: Comparison of Fat and Water References. Journal of Magnetic Resonance Imaging, 43 (1), pp. 203-212. doi:10.1002/jmri.24972

West J, Leinhard OD, Romu T, Collins R, Garrat S, Bell JB, Borga M, Thomas EL (2016) Feasibility of MR-based Body Composition Analysis in Large Scale Population Studies. PLoS ONE 11 (9): e0163332. doi:10.1371/journal.pone.0163332.

Chakravarthy, M. V., Siddiqui, M. S., Forsgren, M. F., Sanyal, A. J. (2020). Harnessing Muscle–Liver Crosstalk to Treat Nonalcoholic Steatohepatitis. Frontiers in Endocrinology, 11, 982. doi:10.3389/fendo.2020.592373

Giambini H, Hatta T, Krzysztof GR, Widholm P, Karlsson A, Leinhard OD, Adkins MC, Zhao C (2017) An Intramuscular Fat Infiltration Evaluated by Magnetic Resonance Imaging Affects the Extensibility of the Supraspinatus Muscle. Muscle Nerve, doi:10.1002/mus.25673.

Romu T, Borga M, Leinhard OD (2011) MANA – Multi Scale Adaptive Normalized Averaging. IEEE International Symposium on Biomedical Imaging: From Nano to Macro,  pp. 361-364. doi:10.1109/ISBI.2011.5872424

Erlingsson S, Herard S, Leinhard OD, Lindström T, Länne T, Borga M and Nystrom F. H (2009) Men Develop More Intra-Abdominal Obesity And Signs Of The Metabolic Syndrome Following Hyper-Alimentation Than Women. Metabolism Journal, 58(7), pp. 995-1001. do: http://dx.doi.org/10.1016/j.metabol.2009.02.028

Borga M (2018), MRI adipose tissue and muscle composition analysis – a review of automation techniques, British Journal of Radiology doi.org/10.1259/bjr.20180252

Dahlqvist, J., Widholm, P., Dahlqvist Leinhard, O., Vissing, J. (2020). MRI in Neuromuscular Diseases: An Emerging Diagnostic Tool and Biomarker for Prognosis and Efficacy. Annals of Neurology. doi.org/10.1002/ana.25804

Linge J, Heymsfield SB, Dahlqvist Leinhard O. (2019) On the Definition of Sarcopenia in the Presence of Aging and Obesity—Initial Results from UK Biobank, The Journals of Gerontology: Series A, glz229, https://doi.org/10.1093/gerona/glz229

Rydell J, Knutsson H, Pettersson J, Johansson A, Farnebäck G, Leinhard OD, Lundberg P, Nyström F, Borga M (2007) Phase Sensitive Reconstruction for Water/Fat Separation in MR Imaging Using Inverse Gradient. In: Ayache N., Ourselin S., Maeder A. (eds) Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007. MICCAI 2007. Lecture Notes in Computer Science, 4791. Springer, Berlin, Heidelberg. doi: https://doi.org/10.1007/978-3-540-75757-3_26

Covarrubias Y, Fowler KJ, Mamidipalli A, Hamilton G, Wolfson T, Leinhard OD, Jacobsen G,  Horgan S,  Schwimmer JB, Reeder SB, Sirlin CB (2019) Pilot study on longitudinal change in pancreatic proton density fat fraction during a weight‐loss surgery program in adults with obesity, Journal of Magnetic Resonance Imaging (JMRI) doi.org/10.1002/jmri.26671

West J, Romu T, Thorell S, Lindblom H, Berin E, Holm A-CS, Åstrand LL, Karlsson A, Borga M, Hammar M, Leinard OD (2018) Precision of MRI-based body composition measurements of postmenopausal women. PLoS ONE 13(2): e0192495. https://doi.org/10.1371/journal.pone.0192495.

Ferguson, L. D., Linge J., Dahlqvist Leinhard, O., Woodward, R., Hall Barrientos, P., Roditi, G., Radjenovic, A., McInnes, I. B., Siebert, S., Sattar, N. (2020). Psoriatic arthritis is associated with adverse body composition predictive of greater coronary heart disease and type 2 diabetes propensity – a cross-sectional study, Rheumatology, doi: https://doi.org/10.1093/rheumatology/keaa604.

Middleton MS, Haufe W, Hooker J, Borga M, Leinhard OD, Romu T, Tunón P, Hamilton G, Wolfson T, Gamst A, Loomba R, Sirlin CB (2017) Quantifying Abdominal Adipose Tissue and Thigh Muscle Volume and Hepatic Proton Density Fat Fraction: Repeatability and Accuracy of an MR Imaging–based, Semiautomated Analysis Method. Radiology 283 (2), pp. 438–449.

Leinhard OD, Johansson A, Rydell J, Smedby Ö, Nyström F, Lundberg P, Borga M (2008) Quantitative Abdominal Fat Estimation Using MRI. Reprint from proceedings of the 19th International Conference on Pattern Recognition (ICPR), art. no. 4761764.

Agebratt C, Ström E, Romu T, Dahlqvist-Leinhard O, Borga M, Leandersson P, Nystrom FH (2016) A Randomized Study of the Effects of Additional Fruit and Nuts Consumption on Hepatic Fat Content, Cardiovascular Risk Factors and Basal Metabolic Rate.  PLoS ONE 11(1): e0147149. https://doi.org/10.1371/journal.pone.0147149.

Borga, M., Ahlgren, A., Romu, T., Widholm, P., Dahlqvist Leinhard, O., West, J. (2020). Reproducibility and repeatability of MRI‐based body composition analysis. Magnetic Resonance in Medicine. doi.org/10.1002/mrm.28360

Romu T, Dahlström N, Leinhard OD, Borga M (2016) Robust Water Fat Separated Dual-Echo MRI by Phase-Sensitive Reconstruction. Magnetic Resonance in Medicine, 78 (3), pp. 1208–1216. doi:10.1002/mrm.26488.

Linge J, Whitcher B, Borga M, Leinhard OD (2019) Sub‐phenotyping Metabolic Disorders Using Body Composition: An Individualized, Nonparametric Approach Utilizing Large Data Sets, Obesity, doi.org/10.1002/oby.22510

Thomas M, Newman D, Leinhard OD, Kasmai B, Greenwood R, Malcolm P, Karlsson A, Rosander J, Borga M, Toms A (2014) Test-Retest Reliability of Automated Whole Body and Compartmental Muscle Volume Measurements on a Wide Bore 3T MR System. European radiology, 24 (9), pp. 2279-2291.

Newman D, Kelly-Morland C, Leinhard OD, Kasmai B, Greenwood R, Malcolm PN, Romu T, Borga M, Toms AP (2016) Test–retest reliability of rapid whole body and compartmental fat volume quantification on a widebore 3T MR system in normal-weight, overweight, and obese subjects. Journal of Magnetic Reasoning Imaging, 44 (6), pp. 1464–1473, doi:10.1002/jmri.25326.

Karlsson, A., Peolsson, A., Elliott, J., Romu, T., Ljunggren, H., Borga, M., & Dahlqvist Leinhard, O. (2019). The relation between local and distal muscle fat infiltration in chronic whiplash using magnetic resonance imaging. PloS one, 14(12), e0226037. doi:10.1371/journal.pone.0226037

Borga M, Thomas EL, Romu T, Rosander J, Fitzpatrick J, Leinhard OD, Bell JD (2015) Validation of a Fast Method for Quantification of Intra‐Abdominal and Subcutaneous Adipose Tissue for Large‐Scale Human Studies. NMR in Biomedicine, 28 (12), pp. 1747-1753.

Ulbrich E, Nanz D, Leinhard OD, Marcon M, Fisher M (2017) Whole-Body Adipose Tissue And Lean Muscle Volumes And Their Distribution Across Gender And Age: MR-Derived Normative Values In A Normal-Weight Swiss Population. Magnetic Resonance in Medicine, doi:10.1002/mrm.26676.