Skip to content
  • Career
  • Support
  • Contact Us
Menu
  • Career
  • Support
  • Contact Us
  • Solutions
    • Clinical Services
    • Research Services
  • Get Started
    • Get Set Up
    • Get a Quote
  • Science
    • What We Do
    • How We Do It
    • Why It Matters
    • Our Core Areas
    • Technology
  • News & Events
    • News
    • Events
  • Resources
    • Webinars
    • Publications
    • Whitepapers
    • Report References
    • Media
  • About Us
    • About AMRA
    • The Team
    • Partners & Investors
Menu
  • Solutions
    • Clinical Services
    • Research Services
  • Get Started
    • Get Set Up
    • Get a Quote
  • Science
    • What We Do
    • How We Do It
    • Why It Matters
    • Our Core Areas
    • Technology
  • News & Events
    • News
    • Events
  • Resources
    • Webinars
    • Publications
    • Whitepapers
    • Report References
    • Media
  • About Us
    • About AMRA
    • The Team
    • Partners & Investors
Search
Close
Menu
  • Solutions
    • Clinical Services
    • Research Services
  • Get Started
    • Get a Quote
    • Get Set Up
  • News & Events
    • News
    • Events
  • Science
    • What We Do
    • How We Do It
    • Why It Matters
    • Our Core Areas
    • Technology
  • Resources
    • Webinars
    • Publications
    • Whitepapers
    • Report References
    • Media
  • About Us
    • About AMRA
    • The Team
    • Partners & Investors
  • Career
  • Support
  • Contact Us
  • All posts

AMRA Medical’s Whole-body MRI Analysis Used in FSHD Clinical Trial Research Network Study for Biomarker Development

  • October 13, 2021

Whole-body MRI will be used in the MOVE+ Natural History Study to develop disease progression biomarkers that enhance future clinical trials for Facioscapulohumeral Muscular Dystrophy (FSHD)

 

LINKÖPING, Sweden, October 13, 2021 — AMRA Medical, a digital health company delivering a new standard in body composition analysis through rapid whole-body magnetic resonance imaging (MRI), today announced its involvement with the Facioscapulohumeral Muscular Dystrophy (FSHD) Clinical Trial Research Network (CTRN) to support the Motor Outcomes to Validate Evaluations Plus (MOVE+) Study—a natural history study for people living with FSHD.

MOVE+ is a sub-study of the ongoing natural history study called Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD) and adds MRI—made possible in part through sponsorship by Avidity Biosciences, FSHD Society, Friends of FSH Research, and FSHD Canada. MOVE+ will enroll 200 participants across 12 sites in the US and two planned sites in Canada with the goal of better understanding how to utilize whole-body MRI to discover and validate specific biomarkers for FSHD that can inform future clinical trials. The results of this study will be particularly important for MOVE+ sponsoring companies like Avidity Biosciences—a biopharmaceutical company developing a new class of RNA therapeutics with an advancing and expanding pipeline that includes multiple skeletal muscle programs.

“The FSHD CTRN is very excited about our collaboration with AMRA. We think that the use of whole-body MRI will be important not only for trial planning, but to better understand and treat people with FSHD,” says Jeffrey Statland, MD, Professor of Neurology at the University of Kansas Medical Center, which also is the Clinical Coordinating Center for the FSHD CTRN.

To date, the MOVE study has used functional tests as primary outcomes, but recent studies have shown the promise of MRI for FSHD. To complement functional tests, MOVE+ will use AMRA’s whole-body, whole-muscle MRI protocol and analysis, which involves measuring 36 muscles throughout the participant’s shoulders, arms, torso and legs—distal to proximal and bilaterally. Specifically, the researchers will quantify muscle fat infiltration, lean muscle volume, and muscle fat fraction at two time points throughout a three-year study period for each individual.

Evaluating entire muscles throughout the whole body provides a fuller picture of how the disease presents and progresses, which is critical to understand when searching for the most optimal outcome measurements to use in FSHD clinical trials. Not only is this applicable for FSHD, but also other neuromuscular disorders including DMD, LGMD, Myotonic Dystrophy, Mitochondrial Myopathy, SBMA, SIBM, and Pompe Disease.

Learn more about AMRA Medical’s MRI-based services for neuromuscular disease clinical trials at amramedical.com/solutions/medical-research-services/ or connect with our team of experts for a detailed discussion at info@amramedical.com.

  • All posts
Research Services
Follow us
Linkedin Twitter Facebook

About

AMRA offers clinical services and research services to support transformative care and vital decision-making, from clinical research to clinical care.

Contact

  • info@amramedical.com
  • +46 (0) 13 16 26 00
  • Contact Our Support
  • Data Privacy Policy
  • Cookie Policy
  • Data Privacy Policy
  • Cookie Policy

Newsletter

    © 2023 AMRA Medical AB

    AMRA Medical
    Manage Cookie Consent
    To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
    Functional Always active
    The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
    Preferences
    The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
    Statistics
    The technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
    Marketing
    The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
    Manage options Manage services Manage vendors Read more about these purposes
    View preferences
    {title} {title} {title}
    AMRA Medical
    Manage Cookie Consent
    To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
    Functional Always active
    The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
    Preferences
    The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
    Statistics
    The technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
    Marketing
    The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
    Manage options Manage services Manage vendors Read more about these purposes
    View preferences
    {title} {title} {title}