Research Services
Metabolic Research Services
Deepen your insights to push your metabolic research and clinical trials forward and understand what is happening to an individual from the inside out. With AMRA’s MRI protocol and precise body composition biomarkers, you can accurately classify and quantify fat and muscle in unparalleled detail.
Advance Clinical Research with AMRA® Researcher
We deliver key insights few others can offer– helping our partners make optimal decisions for research and development. Whether you are conducting a complex mechanistic study or a large-scale, international, multi-center imaging trial, we can get you precise body composition data—with tailored services to meet your exact needs.
AMRA® Researcher software delivers:
- Highly accurate, reproducible and precise MR imaging data
- Global and regional muscle and fat volumes—with accurate anatomical classification
- Contextual disease insights with individualized data
Earlier Insights and Deeper Knowledge
The earlier you get answers in drug R&D, the more equipped you are to make confident decisions on the next steps of your clinical program.
Utilizing multiple fat and muscle biomarkers offers you an unrivalled level of detail that can help you analyze complex metabolic disease processes, the efficacy and impact of a drug, and changes over the course of disease—so you can get the key information you need as early as possible.
Drug Impact and Efficacy
We understand that you need to know if your drug candidate works and if it is safe—as efficiently and economically as possible.
Our services can help you detect treatment efficacy and identify non-responders early.
Further, our precise muscle and fat biomarkers can help you better characterize individuals with metabolic diseases at baseline, monitor interventional effects, and detect small physiological changes throughout the body.
Disease Course and Longitudinal Tracking
Understanding how metabolic diseases develop and change over time is critical for developing top-tier therapeutics. Our body composition biomarkers and automated image analysis can help you expand your team’s knowledge of how metabolic diseases develop and change throughout disease course.
Our technology delivers volumetric muscle and fat measurements—generating a more comprehensive assessment of what is happening throughout the body—unlike other less accurate techniques such as BIA and DXA.
Patient Recruitment and Stratification
Defining inclusion and exclusion criteria can be complex, and finding the right individuals for your clinical trial can be time-consuming—AMRA helps simplify this process.
With our biomarkers, you can easily phenotype and stratify populations to facilitate more appropriate patient recruitment and smaller, more efficient clinical trials.
Effortless & Cloud-Based Digital Health
1. Getting Started
Setup & Verification using
AMRA® Protocol
2. Scanning
Rapid MRI
3. Data Transfer
Safe & Secure
Image Transfer
4. Analysis
Automated Segmentation, Quantification & QA
5. Delivery
Body Composition
Spreadsheet
Improve Patient Outcomes and Patient Experience
Rapid Turnaround
Get your imaging results quickly! Our team of experts and automated analysis of multiple measurements gets you results fast.
Easy Collaboration
Our automated, cloud-based analysis facilitates use by multiple research groups—even for multisite research.
Regulatory Compliant
Get results you can trust. Our solutions are 21 CFR Part 11 Compliant and we ensure quality-controlled, secure data transfers.
Global Sites
With 200+ global imaging sites using our protocol, multicenter clinical trials have never been more accessible and seamless.
5 Body Composition Biomarkers
Get precise fat and muscle measurements with contextual insights—a new standard in body composition analysis.
Neck-to-knee MRI
Assess multiple regions of the body and whole muscles through a single scan to get more insights from your MRI.
Easy Integration
Easily integrate body composition profiling into your research protocols—tell us what you need and we’ll take care of the rest.
Positive Patient Experience
The body composition method is fast and radiation-free, making it quick and safe for study participants.
What you get
Precise MRI-Based Body Composition Biomarkers
For metabolic disease research and clinical trials, we’ve developed 5 precise body composition biomarkers:
- Visceral Adipose Tissue (VAT)
- Abdominal Subcutaneous Adipose Tissue (ASAT)
- Individual Thigh Muscle Volumes (MV)
- Thigh Muscle Fat Infiltration (MFI)
- Liver PDFF
Interested in other biomarkers? Our team continues to develop new measurements and biomarkers using our ever-growing body composition database. Learn more about our biomarkers and how they are used in clinical trials for metabolic disorders.
Our Metabolic Disease Areas of Interest
Is Your Research Area Not Listed? We can still support you! Contact Us to learn more.
Obesity
Diabetes
NASH and NAFLD
Liver Disease
“Wasting” Disorders
Working with AMRA ensures high-quality accurate data acquisition in our clinical studies that will be used to transform patient care for the future.
Ian Neeland, University Hospitals in Cleveland
Derisk Drug R&D for Musculoskeletal Disorders
Need imaging analytics or clinical trial support? Explore our comprehensive research services from pilot study through commercialization. Our team of MRI and clinical experts can help you design your clinical protocol, explore different biomarkers, and interpret your MRI measurements.
Let’s talk
Tell us how you are using MRI for body composition analysis and let’s power the future of medicine together.
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