LINKÖPING, Sweden, March 14, 2025 – AMRA Medical is muscling up for the 2025 Muscular Dystrophy Association’s Clinical and Scientific Conference (MDA 2025), held in Dallas, Texas from March 16-19th! Our very own Per Widholm, MD, Markus Karlsson, PhD, and Leanna Kellerman will be in Dallas this month to share updates on AMRA’s latest research from one of the largest natural history studies to date, validating our unique, MRI-based biomarkers for use as endpoints in upcoming Facioscapulohumeral Muscular Dystrophy (FSHD) trials.
The first abstract, titled “Quantitative Whole-Body MRI Biomarker Relation to Muscle Strength & Function in FSHD Patients”, found that muscle volume and fat content quantified via MRI are strongly linked to measures of muscle strength within individual muscles of participants with FSHD. The researchers also concluded that combining MRI data from multiple individual muscles into composite endpoints may achieve equally strong correlations to more complex functional tasks, such as the 6-minute walk test (6MWT), paving the way for these measures to be used as surrogate biomarkers in FSHD trials.
Additionally, the study aimed to validate these composite MRI-based measures as methods to identify fast-progressing muscles in participants with FSHD. The data from the abstract titled “Natural History of Muscle Volume and Muscle Fat Content Biomarkers in FSHD Based on
Whole-Body Fat-Referenced MRI”, showed these biomarkers to be highly responsive in monitoring progression in FSHD trials, which is notoriously difficult to do in trials of heterogeneous, slowly-progressing diseases such as FSHD.
Come visit with us to learn about these study results and more during the poster sessions from 18:00-20:00 each evening of the Conference!
AMRA remains committed to advancing precision imaging biomarkers that will revolutionize clinical trial design in neuromuscular disease trials, and we are excited to be showcasing our efforts in doing so at MDA 2025.
If you’ll be at the conference, or want to learn more about what we can do for you, feel free to connect with us via info@amramedical.com. We look forward to seeing you there!
About AMRA Medical
AMRA Medical is a health informatics and precision medicine company that is pioneering body composition analysis, providing cutting-edge solutions to advance both clinical research and patient care initiatives. AMRA’s gold-standard technology delivers multiple fat and muscle biomarkers – derived simply from rapid whole-body MRI scans. AMRA is committed to driving transformative care and simplifying vital decision-making in both research and clinical care settings by offering support services via their innovative platform.
Follow AMRA on LinkedIn for the latest updates in fat distribution and muscle composition assessments in disease research.
MEDIA CONTACT INFORMATION
AMRA Medical
Marie Börjesson, VP Brand & Marketing
0046 70 628 1977
marie.borjesson@amramedical.com