Research Services
Imaging Biomarkers
AMRA’s Imaging Biomarkers deliver precise, MRI-based measurements of fat and muscle composition—helping researchers and drug developers unlock deeper insights across metabolic and musculoskeletal clinical trials.
State-of-the-Art Muscle
and Fat Analytics
Our MRI-based fat and muscle analysis measures help scientists and drug development teams across the metabolic and musculoskeletal trial landscape power their studies, and uncover insights hidden within complex study populations. Whether you’re designing your next study or interpreting its outcomes, our imaging biomarkers are designed to support informed measurement decisions — so that you can advance your pipeline with confidence.
Body Composition Quantificaftion
Our Body Composition biomarkers are acquired from a brief, 8-10 minute MRI protocol. And – we’re continuously adding and customizing our measurement offerings to meet your needs.
Body Composition Profile (BCP)
- Visceral Adipose Tissue
- Abdominal Subcutaneous Adipose Tissue
- Thigh Muscle Volume
- Thigh Muscle Fat Infiltration (intramuscular fat)
- Liver PDFF1
Extended Body Composition
- Total Adipose Tissue
- Total Lean Tissue
- Thigh Subcutaneous Adipose Tissue
Extended Muscle Quantification
Additional Muscles: Spinal Erectors, Quadriceps, Hamstrings, Adductors
Extended Organ Quantification
- Liver and Spleen Volume
- Pancreas PDFF1
- Kidney PDFF1 and Sinus Fat Volume
Insights Biomarkers
- AMRA® Muscle and Body Fat Z-Scores
- AMRA® Muscle Assessment Score (MAsS)
- proton density fat fraction
Musculoskeletal Quantification
Using a high-resolution MRI-scan lasting just 45 minutes on average, our musculoskeletal imaging biomarkers provide a detailed overview of muscle health and composition, allowing you to get exactly what you need to power musculoskeletal disease trials.
Muscles
Shoulders & Arms
- Supraspinatus
- Infraspinatus
- Subscapularis
- Teres Minor
- Deltoideus
- Biceps Brachii
- Triceps Brachii
Torso
- Pectoralis Major
- Rhomboideus
- Latissimus Dorsi & Teres Major
- Trapezius
- Serratus Anterior
- Spinal Erectors
Thights
- Quadriceps
- Hamstrings
- Adductors
Lower Legs
- Anterolateral compartment
- Deep Posterior compartment
- Superficial Posterior compartment
- Gastrocnemius Medialis
- Tibialis Anterior
Measurements
Lean Muscle Volume (LMV)
Amount of contractile muscle tissue within the muscle fascia
Muscle Fat Infiltration (MFI)
Fraction of fat in functional muscle tissue
Muscle Fat Fraction (MFF)
Fraction of whole muscle volume occupied by fat
Quality-Control You Can Trust
AMRA’s analyses are 21 CFR Part 11–compliant, ensuring that data integrity and access controls are in line with Good Clinical Practice (GCP). Every scan undergoes dual-operator review to verify image quality and segmentation accuracy, followed by aggregated, study-level quality control to ensure consistency across your dataset—reinforced by a feedback loop to research teams that helps sustain the high standards you expect. This multi-tiered approach ensures the reliability of study-wide findings, and that both the analysis and your measurements are safeguarded.
Contact us for more information