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Research Services

Metabolic Research Services

Deepen your insights to push your metabolic clinical trials forward and understand what is happening to an individual from the inside out. With AMRA’s MRI protocol and precise body composition biomarkers, you can accurately classify and quantify fat and muscle in unparalleled detail.
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Advance Clinical Research with AMRA® Researcher

We deliver key insights few others can offer– helping our partners make optimal decisions for research and development. Whether you are conducting a complex mechanistic study or a large-scale, international, multi-center imaging trial, we can get you precise body composition data—with tailored services to meet your exact needs. The AMRA® Researcher software delivers
  • Highly accurate, reproducible and precise MR imaging data
  • Global and regional fat volumes, fat fractions and lean tissue volumes—with accurate anatomical classification
  • Contextual insights with imaging data compared to normal ranges based on our massive body composition database
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Earlier Insights and Deeper Knowledge
Drug Impact and Efficacy
Disease Course and Longitudinal Tracking
Patient Recruitment and Stratification
Earlier Insights and Deeper Knowledge

Earlier Insights and Deeper Knowledge

The earlier you get answers in drug R&D, the more equipped you are to make confident decisions on the next steps of your clinical program.

Utilizing multiple fat and muscle biomarkers offers you an unrivalled level of detail that can help you analyze complex metabolic disease processes, the efficacy and impact of a drug, and changes over the course of disease—so you can get the key information you need as early as possible.

Drug Impact and Efficacy

Drug Impact and Efficacy

We understand that you need to know if your drug candidate works and if it is safe—as efficiently and economically as possible.

Our services can help you detect treatment efficacy and identify non-responders early.

Further, our precise muscle and fat biomarkers can help you better characterize individuals with metabolic diseases at baseline, monitor interventional effects, and detect small physiological changes throughout the body.

Disease Course and Longitudinal Tracking

Disease Course and Longitudinal Tracking

Understanding how metabolic diseases develop and change over time is critical for developing top-tier therapeutics. Our body composition biomarkers and automated image analysis can help you expand your team’s knowledge of how metabolic diseases develop and change throughout disease course.

Our technology delivers volumetric muscle and fat measurements—generating a more comprehensive assessment of what is happening throughout the body—unlike other less accurate techniques such as BIA and DXA.

Patient Recruitment and Stratification

Patient Recruitment and Stratification

Defining inclusion and exclusion criteria can be complex, and finding the right individuals for your clinical trial can be time-consuming—AMRA helps simplify this process.

With our biomarkers, you can easily phenotype and stratify populations to facilitate more appropriate patient recruitment and smaller, more efficient clinical trials.

Improve Patient Outcomes and Patient Experience

Rapid Turnaround

Get your imaging results quickly! Our team of experts and automated analysis of multiple measurements gets you results fast.

Easy Collaboration

Our automated, cloud-based analysis facilitates use by multiple research groups—even for multisite research.

Regulatory Compliant

Get results you can trust. Our solutions are 21 CFR Part 11 Compliant and we ensure quality-controlled, secure data transfers.

Global Sites

With 200+ global imaging sites using our protocol, multicenter clinical trials have never been more accessible and seamless.

5 Body Composition Biomarkers

Get precise fat and muscle measurements with contextual insights—a new standard in body composition analysis.

Neck-to-knee MRI

Assess multiple regions of the body and whole muscles through a single scan to get more insights from your MRI.

Easy Integration

Easily integrate body composition profiling into your research protocols—tell us what you need and we’ll take care of the rest.

Positive Patient Experience

The body composition method is fast and radiation-free, making it quick and safe for study participants.

Effortless & Cloud-Based Digital Health

1. Getting Started

Setup & Verification using AMRA® Protocol​
2. Scanning
Rapid MRI
3. Data Transfer

Safe & Secure Image Transfer
4. Analysis

Automated Segmentation,
Quantification & QA

5. Delivery

Body Composition
Spreadsheet

What you get

Precise MRI-Based Body Composition Biomarkers

For metabolic disease research and clinical trials, we’ve developed 5 precise body composition biomarkers:
  • Visceral Adipose Tissue (VAT)
  • Abdominal Subcutaneous Adipose Tissue (ASAT)
  • Individual Thigh Muscle Volumes (MV)
  • Thigh Muscle Fat Infiltration (MFI)
  • Liver PDFF
Interested in other biomarkers? Our team continues to develop new measurements and biomarkers using our ever-growing body composition database. Learn more about our biomarkers and how they are used in clinical trials for metabolic disorders.
Contact Our Team To Learn More

Our Metabolic Disease Areas of Interest

Is Your Research Area Not Listed? We can still support you! Contact Us to learn more.

Obesity

Diabetes

NASH and NAFLD

Liver Disease

“Wasting” Disorders

Working with AMRA ensures high-quality accurate data acquisition in our clinical studies that will be used to transform patient care for the future.

Ian Neeland, University Hospitals in Cleveland

Derisk Drug R&D for Metabolic Diseases

Need support on imaging analytics or study design? Check out our suite of time-saving, cost-effective research services. Our team of MRI and clinical experts can help you design your clinical protocol, explore different biomarkers, and interpret your MRI measurements.
Explore

Resources

Publication

Adverse Muscle Composition is Linked to Poor Functional Performance and Metabolic Comorbidities in NAFLD

Webinar

Muscle-Liver Crosstalk and Sarcopenia in Chronic Liver Disease – Novel Techniques and Clinical Evidence

White Paper

Advances in Body Composition: Applications for NASH Clinical Trials

Webinar

Don’t Judge a Body by Its Cover – Body Composition Profiling in Clinical Trials

Let's talk

Tell us how you are using MRI for body composition analysis and let’s power the future of medicine together.

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    AMRA offers clinical services and research services to support transformative care and vital decision-making, from clinical research to clinical care.

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