
Technical validation: AMRA® Researcher
Summary of peer-reviewed publications
Leinhard OD, Johansson A, Rydell J, Smedby Ö, Nyström F, Lundberg P, Borga M, (2008) Quantitative abdominal fat estimation using MRI, Proceedings of 19th International Conference on Pattern Recognition, https://ieeexplore.ieee.org/document/4761764
Romu T, Borga M, Leinhard OD, (2011) MANA – Multi scale adaptive normalized averaging, Proceedings of 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro https://ieeexplore.ieee.org/document/5872424
Andersson T, Romu T, Karlsson A, Noren B, Forsgren MF, Smedby Ö, Kechagias S, Almer S, Lundberg P, Borga M, Leinhard OD, (2015) Consistent intensity inhomogeneity correction in water-fat MRI, J Magn Reson Imaging, https://doi.org/10.1002/jmri.24778
West J, Leinhard OD, Romu T, Collins R, Garratt S, Bell JD, Borga M, Thomas L, (2016) Feasibility of MR-based body composition analysis in large scale population studies, PLoS One, https://doi.org/10.1371/journal.pone.0163332
Borga M, West J, Bell JD, Harvey NC, Romu T, Heymsfield SB, Leinhard OD, (2018) Advanced body composition assessment: From body mass index to body composition profiling, J Investig Med, https://doi.org/10.1136/jim-2018-000722
Thomas MS, Newman D, Leinhard OD, Kasmai B, Greenwood R, Malcolm PN, Karlsson A, Rosander J, Borga M, Toms AP, (2014) Test-retest reliability of automated whole body and compartmental muscle volume measurements on a wide bore 3T MR system, Eur Radiol, https://doi.org/10.1007/s00330-014-3226-6
Borga M, Thomas EL, Romu T, Rosander J, Fitzpatrick J, Leinhard OD, Bell JD, (2015) Validation of a fast method for quantification of intra-abdominal and subcutaneous adipose tissue for large-scale human studies, NMR Biomed, https://doi.org/10.1002/nbm.3432
Karlsson A, Rosander J, Romu T, Tallberg J, Grönqvist A, Borga M, Leinhard OD, (2015) Automatic and quantitative assessment of regional muscle volume by multi-atlas segmentation using whole-body water-fat MRI, J Magn Reson Imaging, https://doi.org/10.1002/jmri.24726
Newman D, Kelly-Morland C, Leinhard OD, Kasmai B, Greenwood R, Malcolm PN, Romu T, Borga M, Toms AP, (2016) Test-retest reliability of rapid whole body and compartmental fat volume quantification on a widebore 3T MR system in normal-weight, overweight, and obese subjects, J Magn Reson Imaging, https://doi.org/10.1002/jmri.25326
Peterson P, Romu T, Brorson H, Leinhard OD, Månsson S, (2016) Fat quantification in skeletal muscle using multi-gradient-echo imaging: Comparison of fat and water references, J Magn Reson Imaging, https://doi.org/10.1002/jmri.24972
Middleton MS, Haufe W, Hooker J, Borga M, Leinhard OD, Romu T, Tunon P, Hamilton G, Wolfson T, Gamst A, Loomba R, Sirlin CB, (2017) Quantifying abdominal adipose tissue and thigh muscle volume and hepatic proton density fat fraction: Repeatability and accuracy of an MR imaging-based, semiautomated analysis method, Radiology, https://doi.org/10.1148/radiol.2017160606
West J, Romu T, Thorell S, Lindblom H, Berin E, Holm AS, Åstrand LL, Karlsson A, Borga M, Hammar M, Leinhard OD, (2018) Precision of MRI-based body composition measurements of postmenopausal women, PLoS One, https://doi.org/10.1371/journal.pone.0192495
Borga M, Ahlgren A, Romu T, Widholm P, Leinhard OD, West J, (2020) Reproducibility and repeatability of MRI-based body composition analysis, Magn Reson Med, https://doi.org/10.1002/mrm.28360
Mandić M, Rullman E, Widholm P, Lilja M, Leinhard OD, Gustafsson T, Lundberg TR, (2020) Automated assessment of regional muscle volume and hypertrophy using MRI, Sci Rep, https://doi.org/10.1038/s41598-020-59267-x
Karlsson A, Peolsson A, Romu T, Leinhard OD, Spetz Holm AC, Thorell S, West J, Borga M, (2021) The effect on precision and T1 bias comparing two flip angles when estimating muscle fat infiltration using fat-referenced chemical shift-encoded imaging, NMR Biomed, https://doi.org/10.1002/nbm.4581
Niklasson E, Borga M, Leinhard OD, Widholm P, Andersson DP, Wiik A, Holmberg M, Brismar TB, Gustafsson T, Lundberg TR, (2022) Assessment of anterior thigh muscle size and fat infiltration using single-slice CT imaging versus automated MRI analysis in adults, Br J Radiol, https://doi.org/10.1259/bjr.20211094
Widholm P, Ahlgren A, Karlsson M, Romu T, Tawil R, Wagner KR, Statland JM, Wang LH, Shieh PB, van Engelen BGM, Cadavid D, Ronco L, Odueyungbo AO, Jiang JG, Mellion ML, Leinhard OD, (2022) Quantitative muscle analysis in facioscapulohumeral muscular dystrophy using whole-body fat-referenced MRI: Protocol development, multicenter feasibility, and repeatability, Muscle Nerve, https://doi.org/10.1002/mus.27638
Nayak KS, Cui SX, Tasdelen B, Yagiz E, Weston S, Zhong X, Ahlgren A, (2023) Body composition profiling at 0.55T: Feasibility and precision, Magn Reson Med, https://doi.org/10.1002/mrm.29682
Heerfordt J, Karlsson M, Kusama M, Ogata S, Mukasa R, Kiyosawa N, Sato N, Widholm P, Leinhard OD, Ahlgren A, Mori-Yoshimura M, (2024) Volumetric muscle composition analysis in sporadic inclusion body myositis using fat-referenced magnetic resonance imaging: Disease pattern, repeatability, and natural progression, Muscle Nerve, https://doi.org/10.1002/mus.28252
Fowler KJ, Venkatesh SK, Obuchowski N, Middleton MS, Chen J, Pepin K, Magnuson J, Brown KJ, Batakis D, Henderson WC, Shankar SS, Kamphaus TN, Pasek A, Calle RA, Sanyal AJ, Loomba R, Ehman R, Samir AE, Sirlin CB, Sherlock SP, (2023) Repeatability of MRI Biomarkers in Nonalcoholic Fatty Liver Disease: The NIMBLE Consortium, Radiology, https://doi.org/10.1148/radiol.231092
Fuchs CJ, Hermans WJH, van den Hurk J, Wiggins CJ, Widholm P, Leinhard OD, Veeraiah P, Wildberger JE, Prompers JJ, van Loon LJC, (2025) Quantifying Leg Muscle Disuse Atrophy During Bed Rest Using DXA, CT, and MRI, Eur J Sport Sci, https://doi.org/10.1002/ejsc.12299